Figure 2
Effects of NBO on MCAO-induced brain damage and behavioral motor deficits. (A)NBO-treated rats (n = 9) had greater total and striatal damage, and showed a trend toward an increase in cortical brain damage, as compared with MCAO control rats treated with medical air (n = 10). Sham animals showed no brain damage (n = 6; data not shown). (B)NBO further increased brain edema and swelling as compared to MCAO control rats treated with medical air. (C)Typical examples of brain slices in MCAO rats treated with either medical air or NBO. Data are expressed as mean ± SEM (mm3). * P< 0.01 vsMCAO control rats treated with medical air.