Application of medical gases in the field of neurobiology

Medical Gas Research

Table 1 Biological Effects and Potential Mechanisms of Helium

BIOLOGICAL EFFECTS	POTENTIAL MECHANISMS
Coronary Collateral Circulation	Prosurvival Signaling Kinases [137]
Improve Exercise Tolerance	MPTP Opening [139]
Anti-Arrhythmic Effect	Mitochondrial Uncoupling [136]
Anti-Tumor Effect	Ca²⁺-Sensitive Potassium Channel [136])
Anti-Inflammation	Reactive Oxygen Species [137, 138]
Hypothermia	Mitochondrial ATP-Regulated K⁺ Channel [139]
High Pressure Nervous Syndrome	Mitochondrial Permeability Transition [139]
Neuroprotective Effect	Opioid Receptors [140]
Myocardioprotective Effect	COX-2 Activity [23]

ISSN: 2045-9912