Table 5 effect of HBOT on other type of cells
From: Hyperbaric oxygen therapy promotes neurogenesis: where do we stand?
Animal model/Cell line | HBO therapy | Method/Duration | Proliferation | Infarct size | Neurobehavioral testing | Mechanism | Institute | Reference |
|---|---|---|---|---|---|---|---|---|
experimental spinal cord injury | Right after injury 100%,2.5 ATA 2 h | D7 | ↑GDNF(+)cell ↑VEGF(+)cell | ↓TTC | ↑BBB locomotor scale | ↓myeloperoxidase (MPO), tumor necrosis factor-a (TNFa) and interleukin-1b (IL-1b) | Taipei Medical University | Tai, et al [8] |
Normal rats | 60%, 1 ATA 3 days | Brdu Single injection | germinative zone ↑Epithelial Cells | / | / | Oxidative stress? | Washington University | Shui et al [9] |
HMEC-1 | 100%, 2.4 ATA 1 h | / | ↑HMEC-1 proliferation | / | / | antioxidant, cytoprotective genes upregulation | University of Connecticut, USA | Godman et al [10] |