Body weight and neurological function. A. Body weight was markedly reduced at 24 h after MCAO when compared with pre-insult body weight and sham animals (#P< 0.05 vs. sham). Hydrogen saline treatment applied at 3 h after reperfusion partially prevented body weight loss (**P< 0.01 vs. MCAO). B. Neurological scores were significantly decreased (higher) after MCAO (#P< 0.05 vs. sham) and hydrogen saline applied at 3 h after reperfusion improved neurological function when compared with MCAO group (**P< 0.01).