Effects of CO insufflation into the colonic lumen on CINC-1 expression. The CINC-1 protein expression level (A) and mRNA level (B) were significantly inhibited in rats treated with CO gas insufflation. Data represent the mean ± SEM of 7 rats. *P < 0.01 relative to sham-operated rats. #P < 0.05 relative to rats with TNBS-induced colitis receiving normal air insufflation.