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Table 2 GLM Coefficients for the different models (Mean ± SD) for predicting lesion development

From: Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models

Models

Bias

T2WI

ADC

iDWI

CBF

CBV

MTT

Tmax

Models Predicting 4 h Lesion Development (during treatment)

Control

-11 ± 1.4§

4.0 ± 1.0§

-4.3 ± 1.3§

9.3 ± 1.2§

-0.9 ± 0.2

0.7 ± 0.1

0.5 ± 0.2

0.07 ± 0.008§

NBO

-17 ± 0.8§

2.0 ± 0.3§

0.10 ± 0.3*§

11 ± 0.5§

-0.4 ± 0.2*§

-0.02 ± 0.2*

0.9 ± 0.2

0.05 ± 0.008§

Models Predicting 24 h Lesion Development (post-treatment)

Control

-3.1 ± 1.0†

8.1 ± 0.8†

-9.1 ± 1.0†

2.3 ± 0.8†

-0.7 ± 0.1

0.5 ± 0.1

0.5 ± 0.1

0.05 ± 0.007†

NBO

-13 ± 0.5†

0.6 ± 0.2†

1.0 ± 0.2†

8.9 ± 0.3†

0.2 ± 0.09†

-0.2 ± 0.08

1.3 ± 0.1

0.1 ± 0.006†

Models Predicting Discharge Lesion Development

Control

-3.4 ± 0.6†

4.2 ± 0.4§

-5.1 ± 0.5§

2.7 ± 0.5†

-0.7 ± 0.1

0.5 ± 0.08

0.9 ± 0.1§†

0.06 ± 0.006

NBO

-8.8 ± 0.3†§

0.3 ± 0.1†

0.7 ± 0.2

6.1 ± 0.2†§

-0.2 ± 0.09*§

-0.06 ± 0.07*

0.9 ± 0.09§

0.1 ± 0.006†

  1. *P > 0.05 Non-significant coefficients
  2. †P < 0.05 vs coefficients of 4 h models, §P < 0.05 vs coefficients of 24 h models
  3. Coefficients for Control- and NBO-models were significantly different (P < 0.05) with the exception of T2WI, iDWI, CBF and Tmax for 4 h and MTT for 1-week time points (displayed in light-gray).