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Table 2 GLM Coefficients for the different models (Mean ± SD) for predicting lesion development

From: Evaluating effects of normobaric oxygen therapy in acute stroke with MRI-based predictive models

Models Bias T2WI ADC iDWI CBF CBV MTT Tmax
Models Predicting 4 h Lesion Development (during treatment)
Control -11 ± 1.4§ 4.0 ± 1.0§ -4.3 ± 1.3§ 9.3 ± 1.2§ -0.9 ± 0.2 0.7 ± 0.1 0.5 ± 0.2 0.07 ± 0.008§
NBO -17 ± 0.8§ 2.0 ± 0.3§ 0.10 ± 0.3*§ 11 ± 0.5§ -0.4 ± 0.2*§ -0.02 ± 0.2* 0.9 ± 0.2 0.05 ± 0.008§
Models Predicting 24 h Lesion Development (post-treatment)
Control -3.1 ± 1.0† 8.1 ± 0.8† -9.1 ± 1.0† 2.3 ± 0.8† -0.7 ± 0.1 0.5 ± 0.1 0.5 ± 0.1 0.05 ± 0.007†
NBO -13 ± 0.5† 0.6 ± 0.2† 1.0 ± 0.2† 8.9 ± 0.3† 0.2 ± 0.09† -0.2 ± 0.08 1.3 ± 0.1 0.1 ± 0.006†
Models Predicting Discharge Lesion Development
Control -3.4 ± 0.6† 4.2 ± 0.4§ -5.1 ± 0.5§ 2.7 ± 0.5† -0.7 ± 0.1 0.5 ± 0.08 0.9 ± 0.1§† 0.06 ± 0.006
NBO -8.8 ± 0.3†§ 0.3 ± 0.1† 0.7 ± 0.2 6.1 ± 0.2†§ -0.2 ± 0.09*§ -0.06 ± 0.07* 0.9 ± 0.09§ 0.1 ± 0.006†
  1. *P > 0.05 Non-significant coefficients
  2. †P < 0.05 vs coefficients of 4 h models, §P < 0.05 vs coefficients of 24 h models
  3. Coefficients for Control- and NBO-models were significantly different (P < 0.05) with the exception of T2WI, iDWI, CBF and Tmax for 4 h and MTT for 1-week time points (displayed in light-gray).