Figure 3
From: In vitroActivation of heme oxygenase-2 by menadione and its analogs
Menadione activated full-length human, recombinant HO-2 similar to rat native HO-2. HO-2 activity was measured as described in Methods using recombinant hHO-2 (open circles) and rat brain microsomes (closed triangles) as the source of HO-2. The abscissa shows drug concentration and ordinate shows HO-2 activity as a percent of control in the absence of added drug (mean ± SD, n = 4).