Medical Gas Research

Table 3 HO-2 activation by naphthoquinones containing aminophenyl-piperidinyl substituents

From: In vitroActivation of heme oxygenase-2 by menadione and its analogs

Structure	HO-2	HO-1	Structure	HO-2	HO-1
	% Act.	% Act.		% Act.	% Act.
7010100239	175	81	7010100237	249	82
7010100238	192	71	7010100234	171	82

Rat HO-1 and HO-2 activities were determined as described in Methods. Test compounds were used at a concentration of 100 μM. Activity is reported as a percentage of activity in the absence of test compound; control = 100%. The 10-digit numbers are Otava catalog numbers.

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ISSN: 2045-9912

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