Medical Gas Research

Table 4 HO-2 activation by naphthoquinones containing 2-phenyl moieties

From: In vitroActivation of heme oxygenase-2 by menadione and its analogs

Structure	HO-2	HO-1	Structure	HO-2	HO-1
	% Act.	% Act.		% Act.	% Act.
SI-859	691	81	SI-2522	484	79
SI-108	643	95	SI-556	455	64
SI-1606	596	84	SI-1186	350	91
SI-102	560	102

HO-1 and HO-2 activities were determined as described in Methods. Test compounds were used at a concentration of 100 μM. Activity is reported as a percentage of activity in the absence of test compound; control = 100%. MOMO is methoxymethyl ether. SI = Sniekus Innovations.

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ISSN: 2045-9912

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