Figure 4
From: The potential dual effects of sevoflurane on AKT/GSK3β signaling pathway
Long sevoflurane treatment decreases the levels of P-GSK3β(ser9) and P-AKT(ser473) in H4 cells. A. Anesthesia with 4% sevoflurane for six hours decreases the levels of P-GSK3β(ser9) and P-AKT(ser473) in the H4 cells as compared to the control condition. There is no significant difference in β-Actin levels in the H4 cells between the sevoflurane anesthesia and control condition. B. Quantification of the Western blot shows that the sevoflurane anesthesia decreases the levels of P-GSK3β(ser9) in the H4 cells as compared to the control condition. C. Quantification of the Western blot shows that the sevoflurane anesthesia decreases the levels of P-AKT(ser473) in the H4 cells as compared to the control condition. N = 6.