Table 1 Patient and perioperative characteristics
|  | Desflurane n = 37 | Sevoflurane n = 47 | p-value |
|---|---|---|---|
Patient characteristics | Â | Â | Â |
Age years | 72.3; 69.8 to 74.4 | 71.9; 70.1 to 73.6 | 0.96 |
Gender # female, male | 24, 13 | 33, 14 | 0.60 |
Body mass index kg/m2 | 26.3; 25.3 to 27.6 | 26.6; 25.3 to 27.6 | 0.99 |
P-POSSUM physiology score | 19.8; 17.4 to 21.7 | 19.1; 17.4 to 21.6 | 0.40 |
ASA physical status # 2, 3, 4 | 14, 23, 0 | 23, 22, 2 | 0.22 |
Comorbid conditions # (%) with | Â | Â | Â |
  Hypertension | 26 (70.3%) | 33 (70.2%) | 0.99 |
  Cardiovascular disease | 5 (13.5%) | 10 (21.3%) | 0.36 |
  Diabetes mellitus | 7 (18.9%) | 6 (12.8%) | 0.44 |
  Renal disease | 4 (10.8%) | 3 (6.4%) | 0.47 |
  Pulmonary disease | 2 (5.4%) | 8 (17.0%) | 0.10 |
Preadmission medications # (%) taking | Â | Â | Â |
  Opioid | 1 (2.7%) | 0 | 0.26 |
  Antihypertensive | 26 (70.3%) | 31 (66.0%) | 0.67 |
  Cardiac | 3 (8.1%) | 1 (2.1%) | 0.20 |
  Antihyperglycemic | 6 (16.2%) | 6 (12.8%) | 0.65 |
  Respiratory | 1 (2.7%) | 7 (14.9%) | 0.06 |
  Hypnotic | 1 (2.7%) | 0 | 0.26 |
Type of procedure performed # (%) | Â | Â | 0.27 |
  Intra-abdominal | 3 (8.1%) | 4 (8.5%) |  |
  Other general surgery | 1 (2.7%) | 3 (6.4%) |  |
  Pelvic (gynecologic or urologic) | 27 (73.0%) | 25 (53.2%) |  |
  Orthopedic | 6 (16.2%) | 15 (31.9%) |  |
Intraoperative characteristics | Â | Â | Â |
Average patient state index | 41.9; 39.0 to 43.8 | 41.0; 37.5 to 44.0 | 0.60 |
Average age adjusted anesthetic minimum alveolar concentration fraction% | 0.82; 0.77 to 0.86 | 0.96; 0.91 to 1.03 | <0.0001 |
Mean arterial blood pressure mmHg | 86.4; 81.3 to 89.6 | 82.5; 80.2 to 86.1 | 0.42 |
Mean arterial blood pressure change from preoperative baseline blood pressure % | −5.7; −10.7 to −0.7% | −9.2; −14.0 to −4.9% | 0.18 |
End tidal carbon dioxide mmHg | 33.6; 33.1 to 34.6 | 33.2; 32.7 to 33.6 | 0.28 |
Pulse oxygen saturation % | 98.4; 98.0 to 99.0 | 98.6; 9.1 to 99.0 | 0.67 |
Anesthesia time minutes | 144; 119 to 170 | 139; 125 to 157 | 0.89 |
Surgery time minutes | 118; 92 to 148 | 119; 108 to 133 | 0.60 |
Emergence time minutes | 7.7; 6.3 to 9.1 | 8.2; 6.9 to 9.6 | 0.51 |
Cough on tracheal extubation # (%) yes | 8 (21.6%) | 12 (25.5%) | 0.68 |
Opioid morphine equivalents mcg/kg/hour | 116.1; 91.1 to 151.2 | 143.2; 110.3 to 165.4 | 0.35 |
Postoperative Characteristics | Â | Â | Â |
Recovery room opioids morphine equivalents mcg/kg | 99.3; 54.7 to 144.6 | 101.6; 78.9 to 145.6 | 0.44 |
Postoperative nausea / vomiting # yes | 18 (48.7%) | 17 (36.2%) | 0.25 |
Recovery room length of stay minutes | 105; 96 to 114 | 102; 91 to 114 | 0.74 |
Hospital length of stay, days | 1.6; 1.1 to 2.0 | 1.4; 1.2 to 2.0 | 0.63 |