Figure 1From: The development of hyperbaric oxygen therapy for skin rejuvenation and treatment of photoagingOverview of possible mechanism used by HBOT to attenuate wrinkle formation from exposure to UVB radiation. UVB irradiation is shown to upregulate pathways that cause wrinkles such as the HIF-1α, neutrophils, and angiogenesis pathways. Hyperoxic condition is shown to inhibit those pathways activated by UVB, which results in decreased wrinkles formation.Back to article page