Figure 3
Na 2 S therapy activates Erk1/2 signaling following MI/R. (A-C) Representative immunoblots and densitometric analysis of the expression of phosphorylated Erk1/2 at Threonine-202/Tyrosine-204 residues and total Erk. (D-F) Representative immunoblots and densitometric analysis of the expression of phosphorylated p90RSK at Threonine residue 359 and total p90RSK. Experiments were conducted with heart homogenates collected from Sham, Vehicle, and Na2S-treated mice following 30 minutes of ischemia and 4 hours of reperfusion. Values are mean ± SEM. *p < 0.05 and ***p < 0.001 vs. Sham.