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  1. Traumatic brain injury (TBI) is a major public health issue. The complexity of TBI has precluded the use of effective therapies. Hyperbaric oxygen therapy (HBOT) has been shown to be neuroprotective in multipl...

    Authors: Lei Huang and Andre Obenaus
    Citation: Medical Gas Research 2011 1:21
  2. The hydrogen sulfide-releasing sildenafil, ACS6, has been demonstrated to inhibit superoxide formation through donating hydrogen sulfide (H2S). We have found that H2S antagonizes homocysteine-induced oxidative st...

    Authors: Xiao-Qing Tang, Rong-Qian Chen, Yan-Kai Ren, Piero Del Soldato, Anna Sparatore, Yuan-Yuan Zhuang, Hen-Rong Fang and Chun-Yan Wang
    Citation: Medical Gas Research 2011 1:20
  3. Molecular hydrogen (H2) functions as an extensive protector against oxidative stress, inflammation and allergic reaction in various biological models and clinical tests; however, its essential mechanisms remain u...

    Authors: Teruyasu Hanaoka, Naomi Kamimura, Takashi Yokota, Shinro Takai and Shigeo Ohta
    Citation: Medical Gas Research 2011 1:18
  4. Previous studies performed in the laboratory have shown that nitrogen narcosis induces a decrease in striatal glutamate and dopamine levels. Although we stimulated the N-methyl-D-aspartate (NMDA) receptor, an ...

    Authors: Nicolas Vallée, Jean-Jacques Rissoe and Jean-Eric Blatteau
    Citation: Medical Gas Research 2011 1:16
  5. Hydrogen gas is neuroprotective in cerebral ischemia animal models. In this study, we tested the neuroprotective effects of hydrogen saline, which is safe and easy to use clinically, in a rat model of middle c...

    Authors: Ying Liu, Wenwu Liu, Xuejun Sun, Runping Li, Qiang Sun, Jianmei Cai, Zhimin Kang, Shijun Lv, John H Zhang and Wei Zhang
    Citation: Medical Gas Research 2011 1:15
  6. Medical gases are pharmaceutical molecules which offer solutions to a wide array of medical needs. This can range from use in burn and stroke victims to hypoxia therapy in children. More specifically however, ...

    Authors: Wenwu Liu, Nikan Khatibi, Aishwarya Sridharan and John H Zhang
    Citation: Medical Gas Research 2011 1:13
  7. In acute stage of cerebral infarction, MRI indices (rDWI & rADC) deteriorate during the first 3-7 days after the ictus and then gradually normalize in approximately 10 days (pseudonormalization time), although...

    Authors: Hirohisa Ono, Yoji Nishijima, Naoto Adachi, Shigekuni Tachibana, Shiroh Chitoku, Shigeo Mukaihara, Masaki Sakamoto, Yohei Kudo, Jun Nakazawa, Kumi Kaneko and Hiroshi Nawashiro
    Citation: Medical Gas Research 2011 1:12
  8. Cancer patients receiving radiotherapy often experience fatigue and impaired quality of life (QOL). Many side effects of radiotherapy are believed to be associated with increased oxidative stress and inflammat...

    Authors: Ki-Mun Kang, Young-Nam Kang, Ihil-Bong Choi, Yeunhwa Gu, Tomohiro Kawamura, Yoshiya Toyoda and Atsunori Nakao
    Citation: Medical Gas Research 2011 1:11
  9. The postoperative cognitive function is impaired in elderly patients after general anaesthesia. The fast recovery after xenon anaesthesia was hypothesized to be advantageous in this scenario. We compared early...

    Authors: Jan Cremer, Christian Stoppe, Astrid V Fahlenkamp, Gereon Schälte, Steffen Rex, Rolf Rossaint and Mark Coburn
    Citation: Medical Gas Research 2011 1:9
  10. The extrinsic apoptotic pathway initiates when a death ligand, such as the Fas ligand, interacts with its cell surface receptor (ie., Fas/CD95), forming a death-inducing signaling complex (DISC). The Fas-dependen...

    Authors: Xue Wang, Yong Wang, Seon-Jin Lee, Hong Pyo Kim, Augustine MK Choi and Stefan W Ryter
    Citation: Medical Gas Research 2011 1:8
  11. Neurosurgical operations cause unavoidable damage to healthy brain tissues. Direct surgical injury as well as surgically induced oxidative stress contributes to the subsequent formation of brain edema. Therefo...

    Authors: Jan M Eckermann, Wanqiu Chen, Vikram Jadhav, Frank PK Hsu, Austin RT Colohan, Jiping Tang and John H Zhang
    Citation: Medical Gas Research 2011 1:7
  12. Besides oxygen, several other gases such as NO, CO, H2, H2S, Xe and O3 have come to age over the past few years. With regards to O3, its mechanisms of action in medicine have been clarified during the last two de...

    Authors: Velio Bocci, Iacopo Zanardi and Valter Travagli
    Citation: Medical Gas Research 2011 1:6
  13. β-Amyloid protein (Aβ) has been shown to potentiate the caspase-3 activation induced by the commonly used inhalation anesthetic isoflurane. However, it is unknown whether reduction in Aβ levels can attenuate t...

    Authors: Yuanlin Dong, Zhipeng Xu, Yiying Zhang, Sayre McAuliffe, Hui Wang, Xia Shen, Yun Yue and Zhongcong Xie
    Citation: Medical Gas Research 2011 1:5
  14. This is an editorial for the inauguration of the Medical Gas Research and addresses a particular issue of using hyperbaric oxygen for stroke treatment.

    Authors: James Toole
    Citation: Medical Gas Research 2011 1:4
  15. The use and benefits of normobaric oxygen (NBO) in patients suffering acute ischemic stroke is still controversial.

    Authors: Benoit Haelewyn, Laurent Chazalviel, Olivier Nicole, Myriam Lecocq, Jean-Jacques Risso and Jacques H Abraini
    Citation: Medical Gas Research 2011 1:2