Medical Gas Research

Table 2 HO-2 activation by naphthoquinones containing furan-benzoxazine moieties

From: In vitroActivation of heme oxygenase-2 by menadione and its analogs

Structure	HO-2	HO-1	Structure	HO-2	HO-1
	% Act.	% Act.		% Act.	% Act.
7114420188	165	39	7114420195	188	26
7114420189	165	32	7114420197	178	51
7114420191	170	29	7114420193	173	69
7114420406	179	28	7114420405	345	85

Rat HO-1 and HO-2 activities were determined as described in Methods. Test compounds were used at a concentration of 100 μM. Activity is reported as a percentage of activity in the absence of test compound; control = 100%. The 10-digit numbers are Otava catalog numbers.

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ISSN: 2045-9912

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