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Table 6 Monohalogenated, monohydroxynaphthoquinones are inactive as HO activators

From: In vitroActivation of heme oxygenase-2 by menadione and its analogs

Structure

HO-2

HO-1

Structure

HO-2

HO-1

 

% Act.

% Act.

 

% Act.

% Act.

7119850429

108

106

SI-441

97

49

  1. HO-1 and HO-2 activities were determined as described in Methods. Test compounds were used at a concentration of 100 μM. Activity is reported as a percentage of activity in the absence of test compound; control = 100%. The 10-digit number is an Otava catalog number; SI = Sniekus Innovations.
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Medical Gas Research

ISSN: 2045-9912

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