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Figure 1 | Medical Gas Research

Figure 1

From: Defining the minimally effective dose and schedule for parenteral hydrogen sulfide: long-term benefits in a rat model of hindlimb ischemia

Figure 1

Na2S Enhances Blood Flow to the Ischemic Hind Limb. Panels A and B are laser doppler blood flow values obtained from the ischemic and nonischemic hindlimbs, respectively, of rats before and after femoral artery ligation. Panel C illustrates changes in blood flow to the ischemic hindlimb minutes after femoral artery ligation, expressed as the ratio of blood flow measured in the ischemic limb (Panel A) vs. the nonischemic limb (Panel B). Panel D illustrates the effect of i.v. administration of Na2S (1 mg/kg, twice daily) on blood flow in the ischemic hindlimb. * p < 0.05 vs Vehicle at respective time point by One Way ANOVA. Values are mean ± SEM.

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